Home / Products / Proteins / Interferons / Human IFN Proteins / Human IFN Alpha 4b (Alpha 4)
Product Features:
Human IFN Alpha 4 recombinant protein expressed in E.coli
Expression induced by viral infection
Encoding gene IFNA4
Ordering
Catalog No.
Pack Size
Price
Quantity
11180-1
1 x 105 units
$280.00
Specifications
Tech Info / Data
Citations
Documentation
Specifications
Formulation
Supplied frozen in phosphate-buffered saline (PBS) containing 0.1% Bovine Serum Albumin (BSA)
Molecular Weight
19.4 kDa
Source
cDNA obtained from human leukocyte mRNA expressed in E.coli
Purity
> 95% by SDS-PAGE stained by Coomassie BlueEndotoxin level < 1 EU/μg
Bioactivity
Measured using a cytopathic inhibition assay on Bovine Kidney Cells (MDBK) with Vesicular Stomatis Virus (VSV); human lung carcinoma cell line A549 with encephalomyocarditis virus (EMCV)
Storage
For retention of full activity store at -70 ºC or below and avoid repeated freeze-thaw cycles
Synonyms
Hu-IFN-α4
Accession Number
X02955
Tech Info / Data
Application Note:
A Comparison of the Binding of Interferon Alpha Subtypes to Isolated IFNAR1 and IFNAR2 with Activity in Antiviral and Antiproliferative Assays (link)
Background:
Recombinant Human Interferon Alpha 4b (alpha 4) obtained from human leukocyte mRNA expressed in E.coli.
IFN alpha 4b is one of the many interferon alpha subtypes belonging to the Type I leukocyte IFN family. The Type I IFN family has antiviral, anti-proliferative and natural killer cell activities.
Citations
1 Citation:
Wilson, Timothy R, et al. (2012). Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature, 12 pgs. PMID: 22763448. (link)