Supplied lyophilized from a 0.2μm filtered solution in phosphate-buffered saline (PBS) containing 5% trehalose
Antigen
Sf21-derived Hu-IFN-α/β R1 extracellular domain
Isotype
IgG1
Host Species
Mouse
Purity
Greater than 95% as determined by protein G affinity chromatographyEndotoxin level <1EU/μg
Specificity
Detects human IFN-alpha/beta R1; in direct ELISAs, this antibody shows no cross reactivity with Hu-IFN-γ R1, Hu-IFN-γ R2, Mu-IFN-α/β R2, Hu-IL-10 Rβ, Hu-IL-10 Rα or Hu-IL-20 Rβ.
Storage
For retention of full activity store at -20oC or below and avoid repeated freeze/thaw cycles
Clone
MMHAR-1
Tech Info / Data
Suggested Applications:
Western Blot: 1 - 2 μg/ml
Flow Cytometry
Direct ELISA: 0.5 - 1.0 μg/ml
Citations
2 Citations:
Guito, Jonathan, et al. (2017). Novel activities by ebolavirus and marburgvirus interferon antagonists revealed using a standardized in vitro reporter system. Virology, 9 pgs. PMID: 27930961. (link)
Fahey, Angela, et al. (2007). Reciprocal effects of IFN-beta and IL-12 on STAT4 activation and cytokine induction in T cells. JLB, 6 pgs. PMID: 17351016. (link)