Home / Products / Proteins / Interferons / Human IFN Proteins / Human IFN Alpha D (Alpha 1)
Product Features:
Human IFN Alpha 1 recombinant protein expressed in E.coli
Expression is induced by viral infection
Encoding gene IFNA1 at position Val114
Ordering
Catalog No.
Pack Size
Price
Quantity
11125-1
1 x 105 units
$280.00
Specifications
Tech Info / Data
Citations
Documentation
Specifications
Formulation
Supplied frozen in phosphate-buffered saline (PBS) containing 0.1% Bovine Serum Albumin (BSA)
Molecular Weight
19.4 kDa
Source
cDNA obtained from human leukocyte mRNA expressed in E.coli
Purity
> 95% by SDS-PAGE stained by Coomassie Blue
Bioactivity
Measured using a cytopathic inhibition assay on Bovine Kidney Cells (MDBK) with Vesicular Stomatis Virus (VSV); human lung carcinoma cell line A549 with encephalomyocarditis virus (EMCV)
Storage
For retention of full activity store at -70 ºC or below and avoid repeated freeze-thaw cycles
Synonyms
Hu-[Val114] IFN-α1
Accession Number
V00538
Tech Info / Data
Background:
Recombinant Human Interferon Alpha D (Hu-IFN-alpha D; Hu-[Val114] IFN-alpha 1) obtained from human leukocyte mRNA expressed in E.coli.
IFN alpha 1 is one of the many interferon alpha subtypes belonging to the Type I leukocyte IFN family. The Type I IFN family has antiviral, anti-proliferative and natural killer cell activities.
Citations
3 Citations:
Wilson, Timothy R, et al. (2012). Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature, 12 pgs. PMID: 22763448. (link)
Wu, TG, et al. (2007). IFN-alpha-induced murine B16 melanoma cancer vaccine cells: induction and accumulation of cell-associated IL-15. Journal of Interferon & Cytokine Research. PMID: 17266439. (link)
Kang, Dong-Chul, et al. (2004). Expression Analysis and Genomic Characterization of Human Melanoma Differentiation Associated Gene-5, mda-5: a Novel Type I Interferon-Responsive Apoptosis-Inducing Gene. Oncogene, 12 pgs. PMID: 14676839. (link)